Nouri weight loss program — vials of compounded semaglutide and tirzepatide

GLP-1 weight loss: compare licensed options

Nouri is an independent publisher. We do not prescribe, dispense, or sell medication, and we are not accepting patients.

  • Published cash prices, read from each company’s own site
  • FDA-approved and compounded, labelled and explained
  • Written for people already on a dose, choosing a refill
Semaglutide from $99/mo
Tirzepatide from $135/mo
How we’re paid

Nouri may earn a commission.

If you sign up with one of the companies we list, we may be paid. It does not change which companies we list, the order they appear in, or the facts we report. LillyDirect pays us nothing. Full disclosure →

Independent publisherNothing for sale herePrices checked September 2026

Compounded GLP-1s are not FDA-approved. Safety info →

2 licensed companies listed, both verified against published criteria

Editorial policy
The basics

What is Nouri’s weight loss program?

There isn’t one any more. Until 2026 Nouri ran a telehealth weight loss program that arranged prescriptions for compounded semaglutide or tirzepatide and shipped them to patients. That program has closed. Nouri is now an independent publisher: we write about GLP-1 weight loss, build free dose calculators, and list the licensed companies that do prescribe — each with its own published cash price and the date we checked it. We do not prescribe, dispense, or sell medication, we hold no patient records from the closed program, and we are not accepting patients. Whether a GLP-1 medication is right for you, and at what dose, is a conversation with a clinician who has evaluated you — this page cannot answer it. Compounded GLP-1s are not FDA-approved.

What changes the price

Three things that decide what you actually pay.

The number a company advertises is almost never the number on your card in month one. Three structural facts explain most of the gap, and all three can be checked before you sign up for anything.

Dose tiering

Some companies price by milligram: the advertised rate is the lowest dose tier, and every titration step raises it. Others charge one rate at any dose. Which one you are buying is usually the largest single difference between two similar-looking prices.

Membership fees

A membership billed separately from the medication turns one advertised price into two line items. Where a published price is all-inclusive of the clinician visit, the medication and shipping, we say so on that company’s entry below.

Commitment length

The lowest published rate almost always requires paying three, six or twelve months up front. Month-to-month costs more per month and is the only rate you can walk away from without forfeiting a balance.

Our method

How we compare providers.

2 companies listed

Licensed, and dispensing through a US pharmacy

Every company on this page is licensed to operate in the United States and dispenses through a state-licensed US pharmacy. We do not list research-peptide sellers, sites that ship without a prescription, or sellers shipping from outside the United States.
— Criterion 1 of 5
5 published criteria

Excluded before any commercial conversation

A company is excluded, whatever it would pay us, if it sells peptides labelled “for research use only”, ships prescription medication without a prescription, ships from outside the United States, will not name the pharmacy that dispenses, or will not put its affiliate terms in writing. We apply the five criteria before any commercial conversation, and we do not name excluded companies — listing a company in order to criticise it is still a claim about that company.
— Criteria 2 to 5
0 paid placements

Nobody can buy a listing, or a position

No company can pay to be listed, to appear higher, or to change how it is described. Entries are listed alphabetically; order is not a ranking. At least one company in every comparison pays us nothing, and it is labelled as such. Prices are re-checked by hand roughly every 90 days — we do not claim live pricing, and every price carries the date we read it.
— Editorial policy

The five criteria, and what a partner can and cannot influence, are published in full on our editorial policy page.

Switching

Before you switch providers.

01

Check what actually transfers.

A prescription written through one telehealth platform does not move to another. Expect a fresh intake and a fresh prescription, not a transfer — and expect that to take time.

Do this first
02

Keep a two-week buffer.

Order the next vial before the current one runs out. A gap of more than a couple of weeks is the most common reason people are restarted at a lower dose and have to titrate back up.

Two weeks of medication
03

Bring your dose, and your concentration.

Write down your last three injection dates, your dose in milligrams, and the mg/mL printed on the vial. Concentration differs between pharmacies, so the units you draw change even when the dose does not — our tirzepatide dose calculator and semaglutide dose calculator convert between them.

Five minutes
A person completes Nouri's online health questionnaire on a tablet at home.
What the research shows

The science is real.

15–20%

average body-weight reduction in clinical trials of the GLP-1 medications semaglutide and tirzepatide — achieved alongside the diet and exercise programmes the trials ran.

Start Average trajectory in clinical studies · STEP 1 / SURMOUNT‑1, with diet & exercise ~14–17 mo

Why the medication is only part of it

  • The medication eases appetite.

    In a clinical trial, semaglutide cut daily calorie intake by about 24% versus placebo — less hunger, fewer cravings.1

  • Protein protects your muscle.

    Enough protein during weight loss preserves lean mass and supports greater fat loss. Whatever you end up paying for medication, this part is free.2

  • Strength training keeps it.

    Resistance training preserves lean muscle while the body loses fat. No company’s price includes it, and no company’s price can substitute for it.3

  • Habits make it last.

    A year after stopping semaglutide, trial participants regained about two-thirds of the weight they had lost — which is worth knowing before you commit to a twelve-month prepaid plan.4

A vial of compounded tirzepatide beside a pre-filled insulin syringe on a warm beige surface
Our standard

Nouri's standard.

What we will publish, what we will not, and what every price on this page has to carry before it appears.

  • Nopaid placements.
  • Nostars, scores, or badges.
  • No“best”, “safest”, or “cheapest”.
  • Noundated prices.
Monthly cost

Monthly cost by provider.

Each company’s own published cash price, read from its site in September 2026. Every company here is licensed to operate in the United States and dispenses through a state-licensed US pharmacy. Listed alphabetically — order is not a ranking. Prices change often; confirm on the company’s site before you buy.

Memberships and hidden fees change the real monthly cost — see which programs charge no membership fee. For providers not listed here, read our reviews and cost breakdowns of Henry Meds, Ivim Health, Mochi Health and Noom Med, or browse the comparisons hub.

Published cash rates, read by hand and dated. We do not claim live pricing.

What we do not list — research-peptide sellers, sites that ship prescription medication without a prescription, sellers shipping from outside the United States, and any company that will not name its dispensing pharmacy or put its affiliate terms in writing. How we choose →

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Compounded tirzepatide is not FDA-approved, has not been evaluated by the FDA for safety, effectiveness or quality, and is not therapeutically equivalent to Zepbound or Mounjaro. Nouri is not affiliated with Eli Lilly and Company or Novo Nordisk; brand names are used only to identify products. Prices are each company’s own published cash rate, read from their site on the date shown. Individual results vary.

Important Safety Information
Questions

Nouri’s weight loss program: common questions

What is Nouri’s weight loss program and how does it work?
Nouri no longer operates a weight loss program. Until 2026 Nouri was a telehealth service that arranged prescriptions for compounded GLP-1 medication and shipped it to patients. That service has closed. Nouri is now an independent publisher: we write about GLP-1 weight loss, build free dose calculators, and list licensed companies that do prescribe, with each company’s own published cash price and the date we checked it. We do not prescribe, dispense, or sell medication, we are not accepting patients, and nothing on this site can be bought. Former patients with a question can write to care@joinnouri.com.
How much does Nouri weight loss cost?
Nothing. Nouri charges nothing for anything on this site — the calculators, the guides and this comparison are free, and there is no account to open. The prices on this page belong to the companies listed, not to Nouri: each is that company’s own published cash rate, read from its site in September 2026. Compounded semaglutide is published from $99/mo and compounded tirzepatide from $135/mo on an annual plan; Zepbound vials bought self-pay through LillyDirect are published from $299/mo at the 2.5 mg dose. Prices change often. Confirm on the company’s own site before you buy.
What is included in the Nouri program?
There is no Nouri program to be included in. What Nouri publishes is free: a tirzepatide dose calculator, a semaglutide dose calculator, cost guides, and this comparison of licensed options. What each company includes in its own price differs, and is stated on its entry above. Some published prices are all-inclusive of the clinician visit, the medication and shipping; others are medication only, with the clinician visit billed separately. That difference is usually larger than the difference between the advertised prices, which is why it sits on the entry rather than in a footnote.
Who qualifies for a GLP-1 weight-loss program?
That is a clinical decision, made by a licensed clinician who has evaluated you — not by this page, and not by an online questionnaire. Broadly, GLP-1 medications for weight management are prescribed to adults who meet body-mass-index and related health criteria, and they are not appropriate for people with a personal or family history of medullary thyroid carcinoma or MEN2, among other contraindications. Nouri cannot tell you whether you qualify, what to take, or at what dose. If you have not been prescribed one of these medications, this comparison is not the page you need.
How much weight can you lose on semaglutide or tirzepatide?
In trials of the brand-name molecules, adults taking semaglutide 2.4 mg with lifestyle support lost a mean of about 14.9% of body weight over 68 weeks (the STEP 1 trial), and those taking tirzepatide 15 mg lost about 20.9% over 72 weeks (the SURMOUNT-1 trial). Those figures come from trials of the branded medications, run alongside diet and exercise. No compounded product has been tested in those trials, and individual results vary. Both trials are cited in full in the references at the foot of this page.
What are the side effects of compounded semaglutide?
The most common GLP-1 side effects are gastrointestinal — nausea, vomiting, diarrhea, constipation and abdominal pain — and they usually ease as the dose is increased gradually. Because compounded medications are not reviewed by the FDA, clinician oversight matters: your prescriber manages your dose and your monitoring, and is the person to tell when something changes. GLP-1s are not for everyone; people with a personal or family history of medullary thyroid carcinoma or MEN2 should not take them. Read the Important Safety Information, and raise anything new with the clinician who prescribed it.
Can I cancel, and how does the Nouri Promise refund work?
The Nouri Promise was a refund term on Nouri’s former telehealth program, which no longer operates, so there is nothing left with Nouri to cancel or refund. Cancellation and refund terms now depend entirely on the company you sign up with, and are set by that company rather than by Nouri. They matter most where a low published rate requires paying six or twelve months up front: find out what happens to the unused balance if you stop, and find out before you pay rather than after.
Are compounded GLP-1s FDA-approved?
No. Compounded semaglutide and tirzepatide are not FDA-approved and are not reviewed by the FDA for safety, effectiveness, or manufacturing quality. They are prepared by a licensed 503A compounding pharmacy against an individual prescription, which is permitted under federal law. They are not equivalent to the FDA-approved brand-name drugs Wegovy, Ozempic, Zepbound, or Mounjaro.

Written by the Nouri Editorial Team · Medically reviewed by Amber Patel, MD · Last reviewed September 15, 2026

References

  1. Blundell J, Finlayson G, Axelsen M, et al. Effects of once-weekly semaglutide on appetite, energy intake, control of eating, food preference and body weight in subjects with obesity. Diabetes Obes Metab. 2017;19(9):1242–1251. doi:10.1111/dom.12932
  2. Wycherley TP, Moran LJ, Clifton PM, Noakes M, Brinkworth GD. Effects of energy-restricted high-protein, low-fat compared with standard-protein, low-fat diets: a meta-analysis of randomized controlled trials. Am J Clin Nutr. 2012;96(6):1281–1298. doi:10.3945/ajcn.112.044321
  3. Lopez P, Taaffe DR, Galvão DA, et al. Resistance training effectiveness on body composition and body weight outcomes in individuals with overweight and obesity across the lifespan: a systematic review and meta-analysis. Obes Rev. 2022;23(5):e13428. doi:10.1111/obr.13428
  4. Wilding JPH, Batterham RL, Davies M, et al. Weight regain and cardiometabolic effects after withdrawal of semaglutide: the STEP 1 trial extension. Diabetes Obes Metab. 2022;24(8):1553–1564. doi:10.1111/dom.14725
  5. Wilding JPH, Batterham RL, Calanna S, et al; STEP 1 Study Group. Once-weekly semaglutide in adults with overweight or obesity. N Engl J Med. 2021;384(11):989–1002. doi:10.1056/NEJMoa2032183
  6. Jastreboff AM, Aronne LJ, Ahmad NN, et al; SURMOUNT-1 Investigators. Tirzepatide once weekly for the treatment of obesity. N Engl J Med. 2022;387(3):205–216. doi:10.1056/NEJMoa2206038
Soft daylight on linen — the quiet of beginning the Nouri program.